19 Comforting Main Dish Casserole Recipes

ByAileen Clark Posted on Updated on
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This list of main dish casserole recipes has everything from tuna casserole to roasted garlic three cheese lasagna. You are sure to find a casserole recipe you love!

I love a good casserole. They are filling, warm, and always seem to taste great. I also love how casseroles are a one dish meal. I can mix everything in one dish, throw it in the oven, and come back in 30-45 minutes to a warm and comforting meal.

4 pictures in a collage of main dish casserole recipes
A picture showing the cover images for all three cookbooks written by Aileen Clark.
Chicken Bacon Casserole
Make this tasty chicken bacon casserole tonight! It's made with flavorful caesar marinated chicken, hearty pasta, and lots of bacon! 
Check out this recipe
A blue casserole dish filed with a casserole made of chicken, pasta, and bacon.
Spinach Lasagna Roll-Ups Recipe
Make this tasty and filling Spinach Lasagna Roll-Ups Recipe tonight! It’s filled with creamy ricotta cheese and fresh spinach and topped with red sauce. 
Check out this recipe
Two spinach lasagna roll-ups on a white plate.
Baked Pesto Chicken Recipe
Make this super simple 2-ingredient baked pesto chicken tonight! You can’t go wrong with flavorful pesto and gooey melted cheese.
Baked Pesto Chicken Recipe on a white plate with a forkful of food.
Sour Cream Chicken Enchiladas
Make a batch of delicious sour cream chicken enchiladas for dinner tonight! This is an easy recipe featuring a sour cream white sauce and no canned soups. These white chicken enchiladas also freeze well so you can even make a double batch.
Check out this recipe
chicken enchiladas in a white sauce sitting in a baking dish.
Taco Stuffed Shells
A delicious spin on classic stuffed shells with taco seasoning, beans, and cheese.
Check out this recipe
Taco Stuffed Shells. This freezer friendly comfort food is shells stuffed with ground turkey, cream cheese, and refried beans. It's topped with salsa, tortilla chips, and cheese. This meal is super kid-friendly and can easily be frozen for a busy a night.
Italian Sausage Stuffed Shells
The ultimate comfort food. Italian Sausage Stuffed Shells is a family favorite!
Check out this recipe
Italian Sausage and Cheese Stuffed Shells Recipes | aileencooks.com
Air Fryer Tater Tot Casserole
This Air Fryer Tater Tot Casserole is full of flavorful layers! It makes for a great meal any day of the week and is incredibly family friendly. Once you whip-up this delicious air fryer recipe, it will quickly become a household favorite.
Check out this recipe
A heaping serving of air fryer tater tot casserole on a fork with the rest of the casserole in the background
Chicken Cordon Bleu Casserole Recipe
Chicken cordon bleu casserole has all of the flavors of chicken cordon bleu in a pasta-based casserole. It's packed with egg noodles, ham, and chicken and topped with melted Swiss cheese and breadcrumbs. Yum!
Check out this recipe
A plate of chicken cordon bleu casserole on a blue and yellow placemat.
Turkey Noodle Casserole Recipe
We are sharing our favorite turkey noodle casserole recipe with you today! You will find directions included for both leftover turkey casserole and ground turkey casserole in this post! We hope you enjoy serving this cheesy turkey casserole to your family. We sure did!  
Check out this recipe
A bite of turkey noodle casserole on a colorful plate.
Cheesy Ranch Chicken and Potato Casserole
Are you looking for an easy chicken and potato casserole recipe? This main dish casserole recipe is for you! It's made with a creamy ranch sauce and topped with gooey cheese.
Check out this recipe
A plate of chicken and potato casserole next to the casserole dish.
Instant Pot Taco Casserole
Taco casserole is nachos in reverse. It’s taco meat cooked in beef gravy and topped with chips and cheese. Then it’s cooked in a casserole that transforms it into a hearty and tasty dinner.
Check out this recipe
A pan of instant pot taco casserole surrounded by a red, white, and blue striped dish towel.
Nacho Cheese Casserole (Freezer Friendly)
Make this delicious and kid-friendly nacho cheese casserole. While you’re at it, try making a double batch and throwing one in the freezer for a busy night!
Check out this recipe
Make this crowd-pleasing nacho cheese taco casserole. It's packed full of taco flavor and topped with delicious nacho cheese!
Chicken and Black Bean Casserole
Chicken and Black Bean Casserole is a hearty casserole filled with brown rice, black beans, chicken, and veggies.
Check out this recipe
The Man Meal (Poor Man’s Steak and Potato Casserole)
The man meal is a baked casserole with red potatoes, hamburger meat, and broccoli. It’s topped with melted cheese and potato chips. Playfully named “the man meal” because it includes the basic food groups – meat and potatoes. 
Check out this recipe
The Man Meal (Poor man's steak and Potato Casserole) on Aileen Cooks
Three Cheese Baked Spaghetti
This cheesy baked spaghetti with sausage is a comforting casserole filled with mozzarella, Parmesan, and ricotta cheeses alongside tasty Italian sausage.
Check out this recipe
Three Cheese Baked Ziti
Delicious baked ziti made with three cheeses! This is the perfect cheesy casserole to make for an a cold night or as a freezer meal.
Check out this recipe
Baked Zucchini Pasta Recipe
Baked Zucchini Pasta is the low-carb version of your favorite Italian dish! It still gives you that cheesy comfort food feeling of a pasta casserole without the heavy pasta. This zucchini pasta bake is a low-carb baked ziti!
Check out this recipe
A casserole dish with a pasta spoon filed with a scoop of zucchini baked ziti.
Creamy Baked Mac and Cheese Recipe
This creamy baked mac and cheese is the perfect grown-up macaroni and cheese. It’s al dente pasta smothered in a creamy cheese sauce made with three different types of cheese. It is the ultimate comfort food that will get you rave reviews!
Check out this recipe
A serving spoon scooping up a heaping scoop of baked white cheddar mac and cheese.
Cheesy Cornbread with Summer Squash
Cheesy Cornbread with Summer Squash is a baked cornbread casserole with grated summer squash (or zucchini) mixed right in. It’s really cheesy and really good!
Tuna Casserole
A classic tuna casserole recipe made just like your grandmother used to make it!
Check out this recipe

We hope you found a main dish casserole recipe you love on this list!

More Main Dish Recipes

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2 Comments

    1. Karen, thank you so much for letting me know my post was broken. It’s all fixed now. You should be able to see all of the casseroles listed.

      Reply